IN-1233 phosphate

CAS No. 1093953-38-8

IN-1233 phosphate( IN1233 | IN 1233 )

Catalog No. M10362 CAS No. 1093953-38-8

A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    IN-1233 phosphate
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM.
  • Description
    A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    IN1233 | IN 1233
  • Pathway
    TGF-beta/Smad
  • Target
    TGFBR
  • Recptor
    TGFBR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1093953-38-8
  • Formula Weight
    517.482
  • Molecular Formula
    C26H24N5O5P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-((4-(6-methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide phosphate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kim JH, et al. Radiology, May 2013 Volume 267, Issue 2, doi.org/10.1148/radiol.121203612. Kim JH, et al. Radiology. 2010 Apr;255(1):75-82.
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